Author

Bryan A. Bogin

Altos LabsORCID 0000-0002-7562-4008Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Organism:rat· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Zachary A. LevineiD· 2 shared Carlos F. LopeziD· 1 shared Federico FontanaiD· 1 shared Michael Irvin· 1 shared Mustafa OzeniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

Zachary A. LevineORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintSep 28, 2026

Folding-Driven Control of the Functional PP1 Complex via Multiscale Modeling

Federico Fontana, Bryan A. Bogin, Michael Irvin…·Carlos F. Lopez

The paper develops a multiscale model to study how conformational dynamics regulate the PP1-GADD34-eIF2 complex, showing folding-dependent assembly enhances biochemical function.

DOI 10.64898/2026.09.23.753607

protein structurestatistical model

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BiophysicsJournal of Chemical Theory and ComputationPeer-reviewedMar 3, 2025

Drugging Disordered Proteins by Conformational Selection to Inform Therapeutic Intervention

Bryan A. Bogin, Zachary A. Levine

This study uses molecular dynamics simulations to investigate how binders of disordered proteins select between different conformations, showing that conformational selection can override sequence specificity in some cases.

5 citations

humanrat

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