Proteasome Inhibition Reduces NBR1 Protein Levels in mATG8-Deficient Cells Independently of Lysosomal Degradation and RAB27A
Cristóbal Cerda‐Troncoso, Eloísa Arias‐Muñoz, Gabriela Vargas, Belén Gaete‐Ramírez, Karina Cereceda, Viviana A. Cavieres, Patricia V. Burgos
The paper shows that proteasome inhibition reduces NBR1 levels in mATG8-deficient cells through a non-lysosomal, RAB27A-independent pathway involving ubiquitin and HRS.
bioRxiv · Jul 15, 2025 · PreprintCell Biology