Author

Louis Kreitmann

Imperial College LondonORCID 0000-0002-7580-9870Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:statistical model· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Alison Helen HolmesiD· 2 shared Jesus Rodriguez-ManzanoiD· 2 shared Ke XuiD· 2 shared Luca MigliettaiD· 2 shared Anirudhha Hazarika· 1 shared Frances BoltiD· 1 shared Karen Brengel-PesceiD· 1 shared Karolina Sobala· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Alison Helen HolmesORCID

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2 papers

Recent·Most cited

Stoichiometric Encoding of Amplification Kinetics Enables High-Level Multiplexing in Single-Channel TaqMan Real-Time PCR

Louis Kreitmann, Kenny Malpartida-Cardenas, Ye Mao, Karolina Sobala, Zexuan Zhao, San Chun Hin, Anirudhha Hazarika, Ke Xu, Luca Miglietta, Zara Breese, Alison H. Holmes, Karen Brengel-Pesce, Laurent Drazek, Jesus Rodriguez-Manzano

This paper introduces a method to increase multiplexing in TaqMan qPCR by encoding target-specific information into amplification curves and decoding them with a transformer model, achieving 8-plex detection with high accuracy.

bioRxiv · Nov 6, 2026 · PreprintMolecular Biology

An adaptive filtering framework for non-specific and inefficient reactions in multiplex digital PCR based on sigmoidal trends

Luca Miglietta, Ke Xu, Priya Chhaya, Louis Kreitmann, Kerri Hill-Cawthorne, Frances Bolt, Alison Helen Holmes, Pantelis Georgiou, Jesús Rodríguez-Manzano

This paper introduces an adaptive filtering framework to improve classification accuracy in multiplex digital PCR by removing non-specific and low-efficient reactions using sigmoidal trends and outlier detection.

bioRxiv · Apr 11, 2022 · PreprintMolecular Biology