Structures of a lipin/Pah phosphatidic acid phosphatase in distinct catalytic states reveal a signature motif for substrate recognition
Tereza Vitkovska, Franceine S. Welcome, Valerie I. Khayyo, Shujuan Gao, Troy Wymore, Michael V. Airola
The paper presents high-resolution structures of Tt Pah2 in different catalytic states, revealing a conserved Asp-Arg motif critical for substrate recognition and catalysis.
Journal of Biological Chemistry · Oct 16, 2025Peer-reviewedBiochemistry