Development of an Ethylenediaminetetraacetic Acid-Enhanced Deep Proteomic Profiling Method for Dried Blood Spots and Its Application in Mouse Disease Models
Daisuke Nakajima, Toshio Kanno, Yusei Okuda, Hiromasa Mitsui, Ryo Konno, Naho Ueyama, Yusuke Endo, Osamu Ohara, Yusuke Kawashima
This paper develops an EDTA-enhanced deep proteomic method for DBS samples, achieving over 7,000 protein identifications and enabling high-throughput analysis in mouse disease models.
bioRxiv · Jul 14, 2026 · PreprintMolecular Biology