A light-induced microprotein triggers regulated intramembrane proteolysis to promote photo sensing in a pathogenic bacterium.
Dimitrios Manias, A. K. Mishra, Jonathan D. Winkelman, Gong Chen, Sampriti Mukherjee
The paper identifies DimA, a microprotein that activates photo-sensing in Pseudomonas aeruginosa by triggering proteolysis of MucA and enhancing algB expression through a positive feedback loop.
Nature Communications · Dec 6, 2025Peer-reviewedMicrobiology