Primate immunodeficiency virus Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex
Leonid Yurkovetskiy, Mehmet Hakan Guney, Kyusik Kim, Shih Lin Goh, Sean Matthew McCauley, Ann Dauphin, William E. Diehl, Jeremy Luban
This study identifies Vpx and Vpr as viral proteins that counteract the HUSH complex to activate provirus transcription in primate immunodeficiency viruses.
Nature Microbiology · Sep 28, 2018Peer-reviewedMolecular Biology