Author

Mehmet Hakan Guney

University of Massachusetts Chan Medical SchoolORCID 0000-0002-9080-7128Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jeremy LubaniD· 2 shared Ann DauphiniD· 1 shared Carl D. NovinaiD· 1 shared David K. YangiD· 1 shared Dustin S. GriesemeriD· 1 shared Hilary K. FinucaneiD· 1 shared Jacob C. UlirschiD· 1 shared James R. XueiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenetics

Jeremy LubanORCID

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2 papers

Recent·Most cited

Genome-wide functional screen of 3'UTR variants uncovers causal variants for human disease and evolution

Dustin S. Griesemer, James R. Xue, Steven K. Reilly, Jacob C. Ulirsch, Kalki Kukreja, Joe R. Davis, Masahiro Kanai, David K. Yang, John C. Butts, Mehmet Hakan Guney, Jeremy Luban, Stephen B. Montgomery, Hilary K. Finucane, Carl D. Novina, Ryan Tewhey, Pardis Christine Sabeti

The paper identifies causal 3'UTR variants linked to human disease and evolution using a new high-throughput assay and functional analysis.

Cell · Sep 1, 2021Peer-reviewedGenetics

Primate immunodeficiency virus Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex

Leonid Yurkovetskiy, Mehmet Hakan Guney, Kyusik Kim, Shih Lin Goh, Sean Matthew McCauley, Ann Dauphin, William E. Diehl, Jeremy Luban

This study identifies Vpx and Vpr as viral proteins that counteract the HUSH complex to activate provirus transcription in primate immunodeficiency viruses.

Nature Microbiology · Sep 28, 2018Peer-reviewedMolecular Biology