Author

Krina Mehta

Leiden UniversityORCID 0000-0002-7621-6436Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

J. G. Coen van HasseltiD· 1 shared Piet H. van der GraafiD· 1 shared Robert S. WallisiD· 1 shared Tingjie GuoiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperSystems Biology

J. G. Coen van HasseltORCID

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1 paper

Recent·Most cited

Systems BiologyAntimicrobial Agents and ChemotherapyPeer-reviewedJul 14, 2022

Quantitative Systems Pharmacology Modeling Framework of Autophagy in Tuberculosis: Application to Adjunctive Metformin Host-Directed Therapy

Krina Mehta, Tingjie Guo, Robert S. Wallis…·J. G. Coen van Hasselt

This paper develops a QSP framework to evaluate metformin's effect on autophagy in tuberculosis, showing limited but dose-dependent benefits in reducing bacterial load and inflammation.

6 citations

mousestatistical model

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