Context effects on repair of 5'-overhang DSB induced by Cas12a in Arabidopsis.
Sébastien Lageix, Miguel Hernández Sánchez-Rebato, Maria Eugenia Gallego, Jérémy Verbeke, Yannick Bidet, Sandrine Viala, Charles I. White
The paper analyzes DNA repair patterns of 5'-overhang DSBs induced by Cas12a in Arabidopsis, showing local end-joining and alternative repair mechanisms in direct repeat contexts.
bioRxiv · Aug 5, 2024 · PreprintGenetics