Author

Antonia M. G. van den Elzen

Yale UniversityORCID 0000-0002-7662-5555Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Carson C. ThoreeniD· 1 shared Daniel B. BurkhardtiD· 1 shared David van DijkiD· 1 shared Guy WolfiD· 1 shared Kevin R. MooniD· 1 shared Kristina Yim· 1 shared Maegan J. Watson· 1 shared Matthew HirniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Carson C. ThoreenORCID

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2 papers

Recent·Most cited

GeneticsPLoS GeneticsPeer-reviewedNov 28, 2022

mRNA 5' terminal sequences drive 200-fold differences in expression through effects on synthesis, translation and decay

Antonia M. G. van den Elzen, Maegan J. Watson, Carson C. Thoreen

The paper identifies how 5' terminal sequences of mRNAs influence expression levels by affecting transcription, translation, and decay, revealing two classes of sequences with distinct regulatory profiles.

12 citations

humanbulk RNA-seq

BioinformaticsNature BiotechnologyPeer-reviewedDec 1, 2019

Visualizing Structure and Transitions for Biological Data Exploration

Kevin R. Moon, David van Dijk, Zheng Wang…·Smita Krishnaswamy

The paper introduces PHATE, a visualization method that captures nonlinear structure in biological data, showing it preserves patterns better than existing tools and reveals novel insights in scRNA-seq data.

1,064 citationstop 1%

humanscRNA-seq