Finding the right fit: A comprehensive evaluation of short-read and long-read sequencing approaches to maximize the utility of clinical microbiome data
Jeanette L. Gehrig, Daniel M. Portik, Mark D. Driscoll, Eric Jackson, Shreyasee Chakraborty, Dawn Gratalo, Meredith Ashby, Ricardo B. Valladares
This paper compares short-read and long-read sequencing approaches for clinical microbiome analysis, finding that long-read methods offer higher taxonomic and functional resolution and better microbial genome recovery.
Microbial Genomics · Mar 1, 2022Peer-reviewedGenomics