Meredith Ashby

Finding the right fit: A comprehensive evaluation of short-read and long-read sequencing approaches to maximize the utility of clinical microbiome data

This paper compares short-read and long-read sequencing approaches for clinical microbiome analysis, finding that long-read methods offer higher taxonomic and functional resolution and better microbial genome recovery.

Establishing reference samples for detection of somatic mutations and germline variants with NGS technologies

The paper establishes reference samples with high-coverage whole-genome sequencing to create truth sets for somatic mutation and germline variant detection using NGS technologies.