Author

Zachary Quinn

Duke UniversityORCID 0000-0002-7688-2914Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein design· 2 Approach:deep learning· 1 Approach:diffusion model· 1 Organism:human· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Pranam ChatterjeeiD· 2 shared Divya Srijay· 1 shared Erin C. O’ConnoriD· 1 shared Jacques Behmoaras· 1 shared Kunal Mishra· 1 shared Leonardo M.R. FerreiraiD· 1 shared Mary Jo Valencia· 1 shared Sophia E. SilveriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSynthetic Biology

Pranam ChatterjeeORCID

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2 papers

Recent·Most cited

Metalorian: De Novo Generation of Heavy Metal-Binding Peptides with Classifier-Guided Diffusion Sampling

Y. Zhang, Divya Srijay, Zachary Quinn, Pranam Chatterjee

Metalorian generates heavy metal-binding peptides using a diffusion model guided by a classifier, producing peptides with controlled specificity and reduced length compared to known proteins.

bioRxiv · Jul 10, 2025 · PreprintSynthetic Biology

moPPIt: De Novo Generation of Motif-Specific and Functionally Active Peptide Binders via Discrete Flow Matching

Tong Chen, Zachary Quinn, Kunal Mishra, Erin C. O’Connor, Sophia E. Silver, Yinuo Zhang, Mary Jo Valencia, Ying Mei, Jacques Behmoaras, Leonardo M.R. Ferreira, Pranam Chatterjee

moPPIt generates motif-specific and functionally active peptide binders using sequence data, validated in vitro and in disease-relevant assays.

bioRxiv · Jul 31, 2024 · PreprintSynthetic Biology