Leonardo M. R. Ferreira

This study shows that acute and lifelong exercise alter the tumorigenic potential and cisplatin susceptibility of lung cancer cells through serological changes.

This study demonstrates that MUC4-targeted CAR-T cells effectively eliminate chemotherapy-resistant CRC cells in vitro and reduce tumor burden in vivo, showing promise for treating chemoresistant colorectal cancer.

This study develops hypoimmunogenic hPSC-derived cardiac organoids that evade immune rejection and repair damaged hearts in animal models.

This study introduces hydroporation as a scalable and efficient method for delivering CAR-T cells, achieving higher yields and viability compared to traditional methods.

This study shows that high-affinity CAR signaling in human Tregs leads to increased cytotoxicity and inflammatory cytokine production, while lower affinity reduces these effects.

moPPIt generates motif-specific and functionally active peptide binders using sequence data, validated in vitro and in disease-relevant assays.