The UBP5 histone H2A deubiquitinase counteracts PRC2-mediated repression to regulate Arabidopsis development and stress responses
James Godwin, Mohan Govindasamy, Nedounsejian Kiruba, Eduardo March, Ronan Halton, Clara Bourbousse, Léa Wolff, Antoine Fort, Michał Krzysztoń, Jesús López Corrales, Szymon Świeżewski, Fredy Barnèche, Daniel S. P. Schubert, Sara Farrona
This study identifies UBP5 as an interactor of PRC2 in Arabidopsis, showing it regulates development and stress responses by counteracting PRC2-mediated repression through H2Aub erasure.
Nature Communications · Jan 22, 2024Peer-reviewedDevelopmental Biology