Jennifer M. Heemstra

This paper develops a method to control gene expression by selectively caging mRNAs with glyoxal, enabling tunable and time-dependent regulation.

The paper develops dsRADAR, a method using ADAR3-derived dsRNA-binding domains to detect and quantify dsRNA with higher sensitivity and specificity than existing antibodies.

This paper introduces EndoVIA 2.0, a method to spatially detect A-to-I RNA editing in FFPE tissues, revealing editing changes in cancer and gastric development.

This paper introduces EndoVIA, a method to spatially visualize A-to-I editing in cells using Endonuclease V immunostaining, enabling quantification and mapping of editing at the nanoscopic level.

The paper introduces a method to selectively isolate A-to-I edited transcripts using Endonuclease V under Ca2+ conditions, improving sensitivity and accuracy for detecting RNA modifications.