Author

Clayton Seitz

Indiana University IndianapolisORCID 0000-0002-7701-5724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1 Approach:variational autoencoder· 1

Frequent Co-Authors

Jing LiuiD· 3 shared Carmella Evans‐MolinaiD· 1 shared Donghong FuiD· 1 shared Hailan Ma· 1 shared Mengyuan LiuiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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3 shared papersBiophysics

Jing LiuORCID

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3 papers

Recent·Most cited

Counting fluorescent emitters with a single photon avalanche diode array

Clayton Seitz, Carmella Evans‐Molina, Jing Liu

This paper introduces a method using SPAD arrays to count fluorophores in widefield microscopy by modeling PCH statistics and performing Bayesian inference.

Scientific Reports · Aug 28, 2026Peer-reviewedBiophysics

Uncertainty-aware localization microscopy by variational diffusion

Clayton Seitz, Jing Liu

This paper introduces a variational diffusion model for uncertainty-aware localization in single-molecule microscopy, enabling high-fidelity super-resolution and uncertainty estimation.

bioRxiv · May 5, 2026 · PreprintBioinformatics

BRD4 phosphorylation regulates the structure of chromatin nanodomains

Clayton Seitz, Donghong Fu, Mengyuan Liu, Hailan Ma, Jing Liu

This study shows BRD4 phosphorylation affects chromatin nanodomain structure through its binding activity, influencing nucleosome dynamics and chromatin organization.

Cells · Jan 9, 2026Peer-reviewedBiophysics