Author

Nicholas Frankiewicz

University of Rochester MedicineORCID 0000-0002-7718-3517Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Christina DavidsoniD· 1 shared Jacquelyn MyersiD· 1 shared Michael BulgeriD· 1 shared Michael R. GetmaniD· 1 shared Paul D. KingsleyiD· 1 shared Sierra FoxiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperGenetics

Christina DavidsonORCID

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1 paper

Recent·Most cited

Hyperacetylated Chromatin Domains Mark Cell Type-Specific Genes and Suggest Distinct Modes of Enhancer Function

Sierra Fox, Jacquelyn Myers, Christina Davidson, Michael R. Getman, Paul D. Kingsley, Nicholas Frankiewicz, Michael Bulger

The paper introduces hyperacetylated chromatin domains (HCDs) as a method to identify cell type-specific genes, finding they outperform super-enhancers in expression and cell identity alignment.

Nature Communications · Sep 11, 2020Peer-reviewedGenetics