Author

Isabel Alfradique‐Dunham

Baylor College of MedicineORCID 0000-0002-7723-2956Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Amanda Stillwell· 2 shared Emily YoungiD· 2 shared Joseph J. JankoviciD· 2 shared Joshua M ShulmaniD· 2 shared Andrew SingletoniD· 1 shared Anita KawiD· 1 shared Anusha Tejomurtula· 1 shared Bo YuaniD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Amanda Stillwell

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Author profile →

3 papers

Recent·Most cited

Parietal Cortex Transcriptomics Refines Parkinson Disease GWAS Nomination and Highlights STAT3 as a Putative Upstream Glial Regulator

Isabel Alfradique‐Dunham, Jessie Sanford, Menghan Liu, Richard J. Perrin, Erin E. Franklin, Scott A. Norris, Paul T. Kotzbauer, Joel S. Perlmutter, John Budde, Carlos Cruchaga, Laura Ibáñez, Miguel Minaya

This study integrates parietal cortex transcriptomics with GWAS data to refine Parkinson's disease risk gene nominations and identify STAT3 as a potential upstream glial regulator.

bioRxiv · Aug 21, 2026 · PreprintNeuroscience

Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes

Isabel Alfradique‐Dunham, Rami Al‐Ouran, Rainer von Coelln, Cornelis Blauwendraat, Emily J. Hill, Lan Luo, Amanda Stillwell, Emily Young, Anita Kaw, Manuela M. X. Tan, Calwing Liao, Dena G. Hernandez, Lasse Pihlstrøm, Donald G. Grosset, Lisa M. Shulman, , Joshua M Shulman

This study identifies genetic associations with Parkinson disease motor subtypes using GWAS, finding novel variants and suggesting overlap with essential tremor genetics.

Neurology Genetics · Apr 1, 2021Peer-reviewedGenomics

Integrated Sequencing & Array Comparative Genomic Hybridization in Familial Parkinson’s Disease

Laurie A. Robak, Renqian Du, Bo Yuan, Shen Gu, Isabel Alfradique‐Dunham, Vismaya Kondapalli, Evelyn Hinojosa, Amanda Stillwell, Emily Young, Chaofan Zhang, Xiaofei Song, Haowei Du, Tomasz Gambin, Shalini N. Jhangiani, Zeynep Coban‐Akdemir, , Joshua M Shulman

The paper combines exome sequencing and array-based comparative genomic hybridization to identify genetic risk factors in familial Parkinson’s disease, finding novel SNVs and CNVs.

bioRxiv · Nov 11, 2019 · PreprintGenetics