Miguel Minaya

This study integrates parietal cortex transcriptomics with GWAS data to refine Parkinson's disease risk gene nominations and identify STAT3 as a potential upstream glial regulator.

The paper identifies lncRNA dysregulation in MAPT mutation carriers and shows the NORAD-pumilio axis modulates tau propagation.

The paper identifies NINL as a modulator of tau aggregation through integrative genomic and functional analyses linking it to proteostasis dysfunction in FTD and AD.

This study shows that a mutation in the MAPT gene disrupts autophagy in neurons, leading to Tau accumulation, and that an autophagy enhancer drug reduces Tau levels.

The paper identifies m6A-dependent circRNA dysregulation as a causal factor in tau-induced neurotoxicity using Drosophila and iPSC models.