Endothelium-on-a-chip for permeability studies in diabetic and diabetic kidney disease milieu
Vika Telle, Pim de Haan, Maciej Grajewski, Patty P. M. F. A. Mulder, Jean-Paul S. H. Mulder, Hiddo J. Lambers-Heerspink, Elisabeth M. J. Verpoorte
This paper describes an endothelium-on-a-chip model to study endothelial barrier permeability in diabetic and diabetic kidney disease conditions, showing protective effects of shear stress and the drug finerenone.
bioRxiv · Sep 22, 2026 · PreprintBioengineering