Mohammad Reza Jabalameli

This study finds that higher polygenic risk scores for breast cancer are associated with longer survival in patients, suggesting a link between genetic predisposition and less aggressive tumors.

This study develops a polygenic score to predict exceptional longevity by modeling pleiotropic genetic variants linked to aging-related traits, showing improved lifespan prediction and identifying potential drug targets.

The paper analyzes 3.6 million individuals to find minimal evidence of non-additive genetic interactions for height.

This paper uses Mendelian randomization to investigate the causal relationship between substance use disorders and severe COVID-19 outcomes, finding a causal role for opioids but a potential negative effect for cannabinoids.

This study identifies genes contributing to beaver longevity and cancer resistance through genomic analysis of gene copy number, expression, and evolutionary changes.

The paper uses exome gene panel sequencing to diagnose syndromic cleft lip/palate patients, finding novel variants in five genes in 36% of cases and highlighting challenges in variant detection due to variable read depth.