Immunogenicity and protective efficacy of a Brucella abortus L7/L12 DNA vaccine delivered via chitosan modified PLGA nanoparticles in mice
Uddhav K. Chaudhari, Satyabrata Dandapat, Sivasankar Panickan, Vimal Kumar, Pradeep Mahadev Sawant
This study evaluates a DNA vaccine against Brucella abortus using chitosan-modified PLGA nanoparticles in mice, showing enhanced immunogenicity and protective efficacy compared to naked DNA.
bioRxiv · Feb 27, 2026 · PreprintMicrobiology