Atanu Maity

Deciphering the role of intrinsically disordered regions of FUS in recognizing U1 snRNA

This study uses molecular dynamics simulations to investigate how the intrinsically disordered regions of FUS recognize U1 snRNA, revealing distinct interaction mechanisms and structural changes upon RNA binding.

Decoding Mutually Induced Conformational Changes in Non-Canonical Recognition of U1 SL4 snRNA by ULD of SF3A1 during Early Spliceosome Assembly

This study investigates the structural and dynamic basis of non-canonical recognition between SF3A1 ULD and U1 snRNA SL4 during spliceosome assembly, revealing dual recognition mechanisms and the impact of mutations on protein-RNA interactions.

Competitive Inhibition of the Nipah Virus Matrix Protein by Conivaptan: From Binding Pocket Dynamics to Protein-Membrane Interactions

This study identifies Conivaptan as a potential inhibitor of the Nipah virus matrix protein by competing with PIP2 for binding and disrupting membrane interactions.

Exploring the effect of Hydrocarbon Cross-linkers on the Structure and Binding of Stapled p53 Peptides

This study uses simulations to analyze how hydrocarbon cross-linkers affect the structure and binding of stapled p53 peptides to MDM2, showing that longer cross-linkers increase rigidity and improve binding efficiency.