Cancer BiologybioRxivPreprint
Agent-based simulations of lung tumour evolution suggest that ongoing cell competition drives realistic clonal expansions
Helena Coggan, James R. Black, Carlos Martínez‐Ruiz…·Nicholas McGranahan
This paper uses agent-based simulations to test models of lung tumour growth, finding that stringent cell competition after tumour size stabilization produces realistic clonal expansions and better estimates of driver mutation effects.
DOI 10.1101/2025.11.04.686578