James R. Black

This paper evaluates the biosecurity risks of generative genome design models by quantifying evolutionary novelty and design efficiency in bacteriophage sequences generated by Evo 2.

This paper uses agent-based simulations to test models of lung tumour growth, finding that stringent cell competition after tumour size stabilization produces realistic clonal expansions and better estimates of driver mutation effects.

This study shows that LIMD1 loss in lung cancer increases PD-L1 expression, promoting immune evasion and enhancing response to immune checkpoint inhibitors.