Author

Kristiana Grigoriadis

University College LondonORCID 0000-0002-8435-0176Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Carlos Martínez‐RuiziD· 1 shared Helena CogganiD· 1 shared James R. BlackiD· 1 shared Jasmin FisheriD· 1 shared Nicholas McGranahaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

Carlos Martínez‐RuizORCID

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1 paper

Recent·Most cited

Agent-based simulations of lung tumour evolution suggest that ongoing cell competition drives realistic clonal expansions

Helena Coggan, James R. Black, Carlos Martínez‐Ruiz, Kristiana Grigoriadis, Jasmin Fisher, Nicholas McGranahan

This paper uses agent-based simulations to test models of lung tumour growth, finding that stringent cell competition after tumour size stabilization produces realistic clonal expansions and better estimates of driver mutation effects.

bioRxiv · Nov 4, 2025 · PreprintCancer Biology