Author

Yuan‐Chen Wang

Second Military Medical UniversityORCID 0000-0002-7839-2564Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Claude FéreciD· 1 shared D.N. CooperiD· 1 shared Emmanuelle GéniniD· 1 shared Emmanuelle MassoniD· 1 shared Jian‐Min CheniD· 1 shared Jiucun WangiD· 1 shared Na PuiD· 1 shared Qi Yang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Claude FérecORCID

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1 paper

Recent·Most cited

GeneticsbioRxivPreprintAug 20, 2026

Context-dependent variant interpretation from Mendelian disease to genetic predisposition: a proof-of-concept using LPL

Qi Yang, Wen‐Bin Zou, Na Pu…·Jian‐Min Chen

This paper proposes a context-dependent framework for variant interpretation by analyzing LPL loss-of-function variants, showing how residual activity levels influence clinical outcomes.

DOI 10.64898/2026.08.12.744351

humanwhole-exome sequencing

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