Author

Qi Yang

Hospital for Sick Children

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Ecology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

Ailong KeiD· 1 shared Akash K. Kaushik· 1 shared Alexandra RasnitsyniD· 1 shared Anders Wilder EricksoniD· 1 shared Andrea Yeh· 1 shared Bryn G. LivingstoniD· 1 shared Calixto-Hope C. LucasiD· 1 shared Chengtao XuiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

Ailong KeORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Context-dependent variant interpretation from Mendelian disease to genetic predisposition: a proof-of-concept using LPL

Qi Yang, Wen‐Bin Zou, Na Pu, Yi Li, Yuepeng Hu, Yuan‐Chen Wang, Xin Liu, Emmanuelle Génin, Emmanuelle Masson, Jiucun Wang, Claude Férec, D.N. Cooper, Weiqin N. Li, Jian‐Min Chen

This paper proposes a context-dependent framework for variant interpretation by analyzing LPL loss-of-function variants, showing how residual activity levels influence clinical outcomes.

bioRxiv · Aug 20, 2026 · PreprintGenetics

Medulloblastoma Forms Symbiotic Metabolic Partnerships with Macrophages to Establish Leptomeningeal Metastases

Vernon Fong, Michelle Ly, Anders Wilder Erickson, Namal Abeysundara, Liam D. Hendrikse, Randy Van Ommeren, Polina Balin, Jigyansa Mishra, Bryn G. Livingston, Patryk Skowron, Olga Sirbu, Ncedile Mankahla, Jiao Zhang, Cory M. Richman, Raul Suarez, , Xiaochong Wu

This study identifies metabolic partnerships between medulloblastoma and macrophages that drive leptomeningeal metastases and suggests targeting the CXCL12-SCARB1-cholesterol axis as a therapeutic strategy.

bioRxiv · Aug 9, 2026 · PreprintCancer Biology

Structure basis for single-strand nucleic acid targeting by IscB and variants

Chengtao Xu, Qi Yang, Xiaolin Niu, Ailong Ke

This paper reports cryo-EM structures of IscB bound to single-stranded nucleic acids, revealing a conformational checkpoint that regulates RNA targeting efficiency and introduces mutations to enhance it.

Nucleic Acids Research · Jun 6, 2026Peer-reviewedBiochemistry

Global patterns, drivers and impacts of metabolic traits across amniotes

Qi Yang, Ziyi Wang, Liqing Fan, Dehua Wang, Fumin Lei, Ying Xiong

This study examines global metabolic trait patterns in amniotes, finding climate-driven variations and links between metabolic rates and diversification/extinction rates.

bioRxiv · Sep 28, 2024 · PreprintEcology