A Subset of G Protein-Coupled Serotonin Receptor Genes is Linked to a Neuronal Gene Expression Signature and Clinically Favorable Biology in IDH-Mutant Gliomas
Flavio Leitao Carvalho-Filho, Henrique Ritter Dal-Pizzol, Gustavo Rassier Isolan, Rafael Roesler
The paper identifies four serotonin receptor genes linked to favorable clinical and molecular features in IDH-mutant lower-grade gliomas, suggesting a neuronal/synaptic differentiation state.
bioRxiv · Aug 27, 2026 · PreprintCancer Biology