Molecular and genetic characterization of sex-linked orange coat color in the domestic cat
Christopher B. Kaelin, Kelly A. McGowan, Joshaya C. Trotman, Donald C. Koroma, Victor A. David, Marilyn A. Menotti-Raymond, Emily C. Graff, Anne Schmidt‐Küntzel, Elena Oancea, Gregory S. Barsh
The paper identifies a 5 kb deletion causing Sex-linked orange coat color in cats by ectopic Arhgap36 expression, which inhibits PKA and disrupts melanogenic pathways downstream of Mc1r.
Current Biology · Jun 1, 2025Peer-reviewedGenetics