Christopher B. Kaelin

The paper identifies a 5 kb deletion causing Sex-linked orange coat color in cats by ectopic Arhgap36 expression, which inhibits PKA and disrupts melanogenic pathways downstream of Mc1r.

The paper analyzes ancestry and selection in Bengal cats using sequencing data to identify genetic factors underlying coat color traits.

The paper identifies the developmental genetics of color pattern establishment in cats by analyzing fetal skin and gene expression, revealing the role of Dkk4 in stripe-like epidermal thickness alterations.

The paper identifies regulatory modules controlling dog color patterns and shows their evolutionary origin in extinct canids.

The paper develops epigenetic clocks and pacemaker models to predict age in plains zebras and other equids using DNA methylation data from blood samples.

This study analyzes tiger genomes to understand their evolutionary history, finding genetic differentiation, recent divergence, and selection pressures in different subspecies.

This study identifies a PEA15 mutation in domestic cats causing lissencephaly and cerebral malformations, revealing a role for PEA15 in gyrencephalic brain development.

The paper presents a chromosome-level genome assembly for the African lion using linked-read, Hi-C, and long-read data, revealing population history insights.