Author

Emily C. Graff

Auburn UniversityORCID 0000-0002-2141-0864Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Christopher B. KaeliniD· 2 shared Gregory S. BarshiD· 2 shared Adam B. KeetoniD· 1 shared Anne Schmidt‐KüntzeliD· 1 shared Asfar Sohail AzmiiD· 1 shared Bassel F. El‐RayesiD· 1 shared Dhana Sekhar Reddy BandiiD· 1 shared Donald C. KoromaiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenetics

Christopher B. KaelinORCID

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3 papers

Recent·Most cited

GeneticsCurrent BiologyPeer-reviewedJun 1, 2025

Molecular and genetic characterization of sex-linked orange coat color in the domestic cat

Christopher B. Kaelin, Kelly A. McGowan, Joshaya C. Trotman…·Gregory S. Barsh

The paper identifies a 5 kb deletion causing Sex-linked orange coat color in cats by ectopic Arhgap36 expression, which inhibits PKA and disrupts melanogenic pathways downstream of Mc1r.

10 citations

mousescRNA-seq

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Cancer BiologyMolecular CancerPeer-reviewedMar 13, 2025

ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma

Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh…·Bassel F. El‐Rayes

ADT-1004, a pan-RAS inhibitor, shows strong antitumor activity in pancreatic ductal adenocarcinoma models with high selectivity and tolerable dosing.

25 citationstop 1%

mouseexperimental assay

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GeneticsPLoS GeneticsPeer-reviewedDec 8, 2020

PEA15 loss of function and defective cerebral development in the domestic cat

Emily C. Graff, J. Nicholas Cochran, Christopher B. Kaelin…·Douglas R. Martin

This study identifies a PEA15 mutation in domestic cats causing lissencephaly and cerebral malformations, revealing a role for PEA15 in gyrencephalic brain development.

8 citations

statistical modelexperimental assay

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