Shivani Thakur

This study investigates the structural and dynamic differences between substrate and intermediate states of Mtb MetRS, revealing how mutations affect enzyme stability and activity.

This study models the binding of initiator and elongator tRNAs to Mtb MetRS during molecular dynamics simulations, revealing differences in their interaction mechanisms.

The paper develops a structure-based computational model to predict virus fitness by analyzing mutations in the SARS-CoV-2 spike protein's binding to ACE2 and antibodies.