Author

Shinya Honda

National Institute of Advanced Industrial Science and TechnologyORCID 0000-0002-7878-3944Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Hiroshi ImamuraiD· 1 shared Takamitsu MiyafusaiD· 1 shared Yota Goto· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 1 mutual co-author link

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1 shared paperBiophysics

Hiroshi ImamuraORCID

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2 papers

Recent·Most cited

BiophysicsFEBS LettersPeer-reviewedMar 17, 2025

Alternatively Folded State of IgG4: Acid-Induced Compaction is Common between IgG1 and IgG4

Hiroshi Imamura, Shinya Honda

This study shows humanized IgG4 can adopt an alternatively folded state under acidic conditions, similar to IgG1, as revealed by SEC-SAXS analysis.

DOI 10.1002/1873-3468.70031

humanexperimental assay

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BiochemistryJournal of Biological ChemistryPeer-reviewedJun 13, 2024

Designing monomeric IFNγ: the significance of domain-swapped dimer structure in IFNγ immune responses

Yota Goto, Takamitsu Miyafusa, Shinya Honda

This study designs a monomeric IFNγ by modifying its domain-swapped dimer structure, showing it retains a similar balance of immunostimulatory and immunosuppressive gene expression as wild-type IFNγ.

1 citation

humanproteomics

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