mGluR5 Negative Modulators for Fragile X: Resistance and Persistence
David C. Stoppel, Patrick K. McCamphill, Rebecca K. Senter, Arnold J. Heynen, Mark F. Bear
This study investigates treatment resistance to mGluR5 NAMs in FXS model mice and shows that brief treatment during a critical period can lead to long-term cognitive improvements.
Frontiers in Psychiatry · Sep 29, 2021Peer-reviewedNeuroscience