Author

David C. Stoppel

Beth Israel Deaconess Medical CenterORCID 0000-0002-5900-9240Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Arnold J. HeyneniD· 1 shared Carrie L. RodrigueziD· 1 shared Ekkehard Matthias KasperiD· 1 shared Ikue Nagakura· 1 shared Jason Shen· 1 shared Jelena Todorovic· 1 shared Mark A. JohnsoniD· 1 shared Mark F. BeariD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Arnold J. HeynenORCID

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2 papers

Recent·Most cited

UBE3A and transsynaptic complex NRXN1-CBLN1-GluD1 in a hypothalamic VMHvl-arcuate feedback circuit regulates aggression

Yi Nong, David C. Stoppel, Mark A. Johnson, Morgane Boillot, Jelena Todorovic, Jason Shen, Xinyu Zhou, Monica J. S. Nadler, Carrie L. Rodriguez, Yuda Huo, Ikue Nagakura, Ekkehard Matthias Kasper, Matthew P. Anderson

The paper identifies a hypothalamic feedback circuit involving UBE3A and the NRXN1-CBLN1-GluD1 complex that regulates aggression, showing how autism-related genetic defects impair this circuit.

bioRxiv · Feb 28, 2023 · PreprintNeuroscience

mGluR5 Negative Modulators for Fragile X: Resistance and Persistence

David C. Stoppel, Patrick K. McCamphill, Rebecca K. Senter, Arnold J. Heynen, Mark F. Bear

This study investigates treatment resistance to mGluR5 NAMs in FXS model mice and shows that brief treatment during a critical period can lead to long-term cognitive improvements.

Frontiers in Psychiatry · Sep 29, 2021Peer-reviewedNeuroscience