GeneticsParasites & VectorsPeer-reviewed
The APL1 immune factor is encoded by a single ancestral gene in most Anopheles species and expanded to three paralogs with distinct function in the Anopheles gambiae complex
Christian Mitri, Emmanuel Bischoff, Karin Eiglmeier…·Michelle M. Riehle
This study identifies APL1 as a single ancestral gene in most Anopheles species and shows its expansion to three paralogs in the Gambiae complex, with distinct functional roles in immunity and malaria transmission.
12 citations