Graça Baltazar

This study compares prolonged mild hypoxia and short severe hypoxia preconditioning of UC-MSCs for neonatal HIE treatment, finding that short severe hypoxia improves functional recovery and alters proteomic pathways related to neural repair.

This study shows that intranasal administration of hypoxia-preconditioned mesenchymal stem cells or their secretome improves recovery in neonatal HIE rats, even at low doses.