Author

João Diego de Agostini Losano

University of FloridaORCID 0000-0002-7947-4027Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bradford W DaigneaultiD· 1 shared MUHAMMAD SAAD SIDDIQUEiD· 1 shared Ramji Kumar BhandariiD· 1 shared Santosh Kumar AnandiD· 1 shared Zongliang JiangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Bradford W DaigneaultORCID

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1 paper

Recent·Most cited

Tetrahydrocannabinol exposure to postejaculatory sperm compromises sperm structure, function, the epigenome, and early embryo development

MUHAMMAD SAAD SIDDIQUE, Santosh Kumar Anand, João Diego de Agostini Losano, Zongliang Jiang, Ramji Kumar Bhandari, Bradford W Daigneault

This study shows that THC exposure to postejaculatory sperm reduces motility, damages DNA, impairs acrosome integrity, alters the methylome, and decreases embryo development potential.

bioRxiv · Mar 24, 2026 · PreprintCell Biology