cfMethDB compiles 4828 cfDNA methylation datasets, identifies 1,048,770 DMCs as potential cancer biomarkers, and provides tools for biomarker discovery and analysis.

Genomics Proteomics & Bioinformatics · Oct 14, 2025Peer-reviewedGenomics

DNA Methylation (DM) data format and DMtools for efficient DNA methylation data storage and analysis

Qiangwei Zhou, Cong Zhou, Zhixian Zhu, Yuanhui Sun, Guoliang Li

The paper introduces a new DNA methylation data format and associated tools to reduce storage and improve analysis efficiency.

bioRxiv · Nov 27, 2023 · PreprintBioinformatics

AraENCODE: a comprehensive epigenomic database of Arabidopsis Thaliana

Zhenji Wang, Minghao Liu, Fuming Lai, Qiangqiang Fu, Liang Xie, Yaping Fang, Qiangwei Zhou, Guoliang Li

AraENCODE provides a comprehensive epigenomic database for Arabidopsis thaliana with 4,511 datasets and integrated resources for studying epigenetic regulation.

bioRxiv · Jun 10, 2023 · PreprintBioinformatics

Chromatin interaction analysis with updated ChIA-PET Tool (V3)

Guoliang Li, Tongkai Sun, Huidan Chang, Liuyang Cai, Ping Hong, Qiangwei Zhou

The paper updates the ChIA-PET Tool (V3) for analyzing ChIA-PET data, showing improved performance in detecting chromatin interactions compared to existing tools.

Genes · Jul 22, 2019Peer-reviewedGenomics