Xionghui Zhou

cfMethDB compiles 4828 cfDNA methylation datasets, identifies 1,048,770 DMCs as potential cancer biomarkers, and provides tools for biomarker discovery and analysis.

This paper introduces FSM, a method to predict effective drug combinations by analyzing drug 'friendship' features, showing improved performance and lower toxicity.

The paper develops a method to identify cell-free DNA fragmentation hotspots in plasma whole-genome sequencing and shows their utility in detecting early-stage cancers with high specificity and sensitivity.