Advancing Protein Ensemble Predictions Across the Order-Disorder Continuum
Michele Invernizzi, Sandro Bottaro, Julian O. Streit, Bruno Trentini, Niccolò Alberto Elia Venanzi, Danny Reidenbach, Youhan Lee, Christian Dallago, Hassan Sirelkhatim, Bowen Jing, Fabio Airoldi, Kresten Lindorff‐Larsen, Carlo Fisicaro, Kamil Tamiola
The paper introduces a benchmark for evaluating protein ensemble generators across ordered and disordered proteins and presents a new model that improves performance on disordered regions.
bioRxiv · Oct 18, 2025 · PreprintBiophysics