Kamil Tamiola

This paper introduces OPES multithermal sampling to efficiently explore rare conformations in intrinsically disordered proteins, revealing transient tertiary structures in ACTR.

The paper introduces a benchmark for evaluating protein ensemble generators across ordered and disordered proteins and presents a new model that improves performance on disordered regions.

The paper improves protein stability prediction by modifying existing models with a self-derived term, enhancing their performance without additional training or data.

ADOPT predicts protein intrinsic disorder using a deep bidirectional transformer, outperforming existing methods in speed and accuracy.

NeRFax converts internal coordinates to Cartesian coordinates efficiently, achieving significant performance gains over existing methods in peptide and biomolecular condensate reconstructions.