Kim Bartels

Structural basis of substrate recognition and transport in bacterial ACS transporters

This study identifies substrate specificity of bacterial ACS transporters using genetics, biochemistry, and structural biology, revealing structural determinants of stereoselectivity in LgoT.

Cefdinir binding to a class-A β-lactamase revealed by serial cryo-crystallography

The paper reports the X-ray crystallographic structure of Cefdinir-bound CTX-M-14 E166A mutant using serial cryo-crystallography.

Binding mode of isoxazolyl penicillins to a Class-A beta-lactamase at ambient conditions

The paper determines the binding modes of three isoxazolyl penicillins to a class-A beta-lactamase at near physiological temperatures using crystallography.

Model-free photon analysis of diffusion-based single-molecule FRET experiments

The paper introduces a model-free method to analyze diffusion-based single-molecule FRET experiments, showing it accurately captures protein dynamics without artifacts from photon trajectory length or diffusion.