Author

Hagen Hofmann

Weizmann Institute of ScienceORCID 0000-0003-1669-3158Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Gabriel RosenblumiD· 2 shared Ivan TerteroviD· 2 shared Christian LöwiD· 1 shared Daniel NettelsiD· 1 shared Giuliano SiligardiiD· 1 shared Itay CarmeliD· 1 shared Kim BartelsiD· 1 shared Nadav EladiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

Gabriel RosenblumORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintMar 18, 2026

Protein disorder controls allostery in DNA

Gabriel Rosenblum, Ivan Terterov, Sujeet Kumar Mishra…·Hagen Hofmann

The paper shows that intrinsically disordered regions in proteins amplify DNA structural fluctuations, enabling allostery in transcription factor binding.

DOI 10.64898/2026.03.17.710445

DNA methylationexperimental assay

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedJul 1, 2025

Model-free photon analysis of diffusion-based single-molecule FRET experiments

Ivan Terterov, Daniel Nettels, Tanya Lastiza-Male…·Hagen Hofmann

The paper introduces a model-free method to analyze diffusion-based single-molecule FRET experiments, showing it accurately captures protein dynamics without artifacts from photon trajectory length or diffusion.

9 citations

fluorescence / live-cell microscopystatistical model

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