Patient-derived glioblastoma neurosphere cultures differentially express nicotinic acetylcholine receptors depending on ambient choline
Elena A. Gondarenko, Diana V. Mazur, Marina Masliakova, Ya. A. Ryabukha, Igor E. Kasheverov, Victor I. Tsetlin, Denis S. Kudryavtsev, Н. В. Антипова
The paper shows that patient-derived glioblastoma neurosphere cultures express nicotinic acetylcholine receptors (nAChRs) 1*, 7, and 9, and their expression and function vary with choline levels in the culture environment.
bioRxiv · Apr 6, 2023 · PreprintMolecular Biology