Author

Suming Chen

Johns Hopkins UniversityORCID 0000-0002-8017-0282Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Arianna Franca AnzmanniD· 1 shared Courtney E. Woods· 1 shared David L. ValleiD· 1 shared Débora Romeo BertolaiD· 1 shared Felicity A. Collins· 1 shared Guilherme Lopes YamamotoiD· 1 shared Jian Ping SuniD· 1 shared John ChristodoulouiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Arianna Franca AnzmannORCID

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2 papers

Recent·Most cited

High-Coverage Four-Dimensional Data-Independent Acquisition Proteomics and Phosphoproteomics Enabled by Deep Learning-Driven Multi-Dimensional Prediction

Moran Chen, Pujia Zhu, Pengfei Wu, Yanhong Hao, Zhourui Zhang, Jian Ping Sun, Wenjing Nie, Suming Chen

This paper develops a deep learning model to predict peptide properties for 4D DIA proteomics, improving protein and phosphorylated protein identification in HeLa cells.

bioRxiv · Jun 12, 2022 · PreprintBioinformatics

Loss of function variants in PCYT1A causing spondylometaphyseal dysplasia with cone/rod dystrophy have broad consequences on lipid metabolism, chondrocyte differentiation, and lipid droplet formation.

Julie A. Jurgens, Suming Chen, Nara Lygia de Macena Sobreira, Sarah Robbins, Arianna Franca Anzmann, Raha Maryam Dastgheyb, Saja S. Khuder, Julie Elizabeth Hoover-Fong, Courtney E. Woods, Felicity A. Collins, John Christodoulou, Guilherme Lopes Yamamoto, Débora Romeo Bertola, Wagner Antonio da Rosa Baratela, Sophie D. Curie, , David L. Valle

This study investigates the effects of PCYT1A variants on lipid metabolism, chondrocyte differentiation, and lipid droplet formation using cellular models and lipidomics.

bioRxiv · Dec 19, 2019 · PreprintGenetics