Author

Saja S. Khuder

Johns Hopkins UniversityORCID 0000-0001-9101-3744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Norman J. HaugheyiD· 2 shared Ajit G. ThomasiD· 1 shared Amit AgarwaliD· 1 shared Arianna Franca AnzmanniD· 1 shared Barbara Stauch SlusheriD· 1 shared Camilo J. RojasiD· 1 shared Courtney E. Woods· 1 shared David L. ValleiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Norman J. HaugheyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Loss of function variants in PCYT1A causing spondylometaphyseal dysplasia with cone/rod dystrophy have broad consequences on lipid metabolism, chondrocyte differentiation, and lipid droplet formation.

Julie A. Jurgens, Suming Chen, Nara Lygia de Macena Sobreira, Sarah Robbins, Arianna Franca Anzmann, Raha Maryam Dastgheyb, Saja S. Khuder, Julie Elizabeth Hoover-Fong, Courtney E. Woods, Felicity A. Collins, John Christodoulou, Guilherme Lopes Yamamoto, Débora Romeo Bertola, Wagner Antonio da Rosa Baratela, Sophie D. Curie, , David L. Valle

This study investigates the effects of PCYT1A variants on lipid metabolism, chondrocyte differentiation, and lipid droplet formation using cellular models and lipidomics.

bioRxiv · Dec 19, 2019 · PreprintGenetics

Inhibition of neutral sphingomyelinase-2 facilitates remyelination

Seung-Wan Yoo, Amit Agarwal, Matthew D. Smith, Saja S. Khuder, Emily G. Baxi, Ajit G. Thomas, Camilo J. Rojas, Mohammed Moniruzzman, Barbara Stauch Slusher, Dwight E. Bergles, Peter A. Calabresi, Norman J. Haughey

This study shows that inhibiting nSMase2 improves myelin quality by protecting oligodendrocytes during remyelination.

bioRxiv · Jun 28, 2019 · PreprintMolecular Biology